Memory stem T cells generated by Wnt signaling from blood of human renal clear cell carcinoma patients

Abstract

The finding that Tscm can accumulate by Wnt signaling <i>in vitro</i> in blood from RCC patients will help in devising new cancer therapy strategies of Tscm-based adoptive immunotherapy, such as dendritic cell-stimulated Tscm, and T cell receptor or chimeric antigen receptor-engineered Tscm.