Sun Protective Potential and Physical Stability of Herbal Sunscreen Developed from Afghan Medicinal Plants

Abstract

OBJECTIVES: The aim of this study was to develop an herbal topical sunscreen formulation based on some fixed oils in combination with some medicinal plants. MATERIALS AND METHODS: purified extract (EAPE), sesame oil, and sea buckthorn oil were selected for the development of the sunscreen formulation. The developed sunscreen formulations containing different concentration of EAPE were evaluated for their different physicochemical properties and stability. RESULTS: The results of the phytochemical analysis revealed the presence of phenolic compounds and flavonoids in all tested extracts. EAPE, sesame oil, and sea buckthorn oil showed the highest absorption in the ultraviolet region. The sun protection factor (SPF) value of the developed formulations containing different concentration of EAPE was in the range of 6.37±0.14 to 21.05±0.85. The sunscreen formulation containing 6% EAPE was stable for 8 weeks in an oven (40 °C) and refrigerator (4 °C). CONCLUSION: studies are highly recommended to prove further the safety and efficacy of our developed sunscreen formulation.