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Lactic acidosis caused by repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the pyruvate dehydrogenase (PDH)–PDH kinase axis

Lactic AcidosisBiochemistryMitochondrial FunctionNatural SciencesPhysiologyCatabolismMolecular BiologyPyruvate DehydrogenaseMitochondrial BiologyKinase AxisMetabolismMedicineRedox BiologyProtein PhosphorylationOxidative Stress