Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies

Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors.

Rakesh K. Jain · PubMed · 1990 · 577 citations

Tumor Biology, Tumor Immunology, Immunocytochemical Technique +15

Phase I Study of ⁶⁸Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma

Marleen Keyaerts, Catarina Xavier, Johannes Heemskerk et al. · Journal of Nuclear Medicine · 2015 · 419 citations · Full text

Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies

Rob C. Roovers, Toon Laeremans, Lieven Huang et al. · Cancer Immunology Immunotherapy · 2006 · 338 citations · Full text

Nanomedicine, Tumor Biology, Tumour Growth +10

Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective <i>In Vivo</i> Imaging of Tumor-Associated Macrophages

Kiavash Movahedi, Steve Schoonooghe, Damya Laoui et al. · Cancer Research · 2012 · 280 citations

Isolation of antigen specific Llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

Leon Frenken, Richard H.J van der Linden, Pim Hermans et al. · Journal of Biotechnology · 2000 · 270 citations

Saccharomyces Cerevisiae, Pathogenesis, Immunology +9