Rob C. Roovers

A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies

Hans J. de Haard, Nicole van Neer, Anneke W. Reurs et al. · Journal of Biological Chemistry · 1999 · 533 citations · Full text

Pharmacy, Biochemistry, Biotechnology +17

Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor

Dietmar M. Zaiss, Jorg van Loosdregt, Andrea Gorlani et al. · Immunity · 2013 · 405 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies

Rob C. Roovers, Toon Laeremans, Lieven Huang et al. · Cancer Immunology Immunotherapy · 2006 · 344 citations · Full text

Medicine, Cancer Biology, Oncology +14

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

Shalini T. Low-Nam, Keith A. Lidke, Patrick J. Cutler et al. · Nature Structural & Molecular Biology · 2011 · 286 citations

Life Sciences, Biochemistry, Molecular Biology +16

A biparatopic anti‐EGFR nanobody efficiently inhibits solid tumour growth

Rob C. Roovers, Maria J.W.D. Vosjan, Toon Laeremans et al. · International Journal of Cancer · 2011 · 278 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17