Isolation of antigen specific Llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

Leon Frenken, Richard H.J van der Linden, Pim Hermans, +4

Journal of Biotechnology

Saccharomyces CerevisiaePathogenesisImmunologyHumoral ResponseImmunodominance +7

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

Rinse Klooster, Jaap J. Plomp, Maartje G. Huijbers, +11

Brain

Camelid Heavy-Chain Variable Domains Provide Efficient Combining Sites to Haptens

Silvia Spinelli, Leon Frenken, Pim Hermans, +4

Biochemistry

Dimeric HaptenCrystal StructureEngineeringProtein AssemblyMolecular Biology +14

Lactobacilli Expressing Variable Domain of Llama Heavy‐Chain Antibody Fragments (Lactobodies) Confer Protection against Rotavirus‐Induced Diarrhea

Neha Pant, Anna Hultberg, Yaofeng Zhao, +10

The Journal of Infectious Diseases

Reduction in morbidity of rotavirus induced diarrhoea in mice by yeast produced monovalent llama-derived antibody fragments

Jacob P. Vandervaart, Neha Pant, Danielle Wolvers, +6

Vaccine

PathogenesisViral PathogenesisImmunologyHumoral ResponseVirology +3

Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments

June Ereño‐Orbea, Taylor Sicard, Hong Cui, +3

Journal of Molecular Biology

BiochemistryProtein AssemblyProtein FoldingNatural SciencesProtein X-ray Crystallography +8

Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal ‘C-tag’

Jing Jin, Kathryn A. Hjerrild, Sarah E. Silk, +16

International Journal for Parasitology

Improved anti-IgG and HSA affinity ligands: Clinical application of VHH antibody technology

Rinse Klooster, Bram Maassen, Jord C. Stam, +6

Journal of Immunological Methods

AllergyVhh Antibody TechnologyImmunologyClinical ApplicationHsa Affinity +4

Lactobacilli Producing Bispecific Llama-Derived Anti-Rotavirus Proteins <i>in vivo</i> for Rotavirus-Induced Diarrhea

Neha Pant, Harold Marcotte, Pim Hermans, +4

Future Microbiology

Development of a novel affinity chromatography resin for platform purification of lambda fabs

Nora Eifler, Giovanni Medaglia, Oliver Anderka, +2

Biotechnology Progress

EngineeringImmunologyLambda FabsProtein PurificationBioanalysis +16