Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

Life Sciences, Genetics, Molecular Genetics +16

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Robin Sherrington, Yuh‐Jin Liang, Ekaterina Rogaeva et al. · Nature · 1995 · 4K citations

Life Sciences, Genetics, Molecular Genetics +14

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Ephrat Levy‐Lahad, Wilma Wasco, Parvoneh Poorkaj et al. · Science · 1995 · 2.6K citations

Life Sciences, Genetics, Molecular Genetics +14

Early-Onset Autosomal Dominant Alzheimer Disease: Prevalence, Genetic Heterogeneity, and Mutation Spectrum

Dominique Campion, Cécile Dumanchin, Didier Hannequin et al. · The American Journal of Human Genetics · 1999 · 788 citations · Full text

Life Sciences, Genetics, Neurology +16