Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer’s Disease and Systemic Inflammation

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

Tyler K. Ulland, Wilbur M. Song, Stanley Ching‐Cheng Huang et al. · Cell · 2017 · 1.3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2

Kazuya Takahashi, Christian D.P. Rochford, Harald Neumann · The Journal of Experimental Medicine · 2005 · 1.1K citations · Full text

Life Sciences, Immunology, Neuroscience +17

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang, Tyler K. Ulland, Jason D. Ulrich et al. · The Journal of Experimental Medicine · 2016 · 882 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Cutting Edge: TREM-2 Attenuates Macrophage Activation

Isaiah R. Turnbull, Susan Gilfillan, Marina Cella et al. · The Journal of Immunology · 2006 · 731 citations · Full text

Life Sciences, Immunology, Molecular Biology +17