Concepedia

DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer

Qi Zhang, Ze-Yan Zhang, Huan Du, Shangze Li, Rongfu Tu, Yifan Jia, Zhe Zheng, Xuemin Song, Run‐Lei Du, Xiaodong Zhang

Cell Death and Differentiation · 2019 · 115 citations · 55 references

Open access

Concepts

MedicineMolecular BiologyOncologyChemotherapyMolecular OncologyNeoplasiaApoptosis ResistanceCancer Cell SignalingChemotherapy ResistanceColorectal CancerSignal Transduction In CancerTherapeutic ResistanceColorectal Cancer ChemopreventionNrf2 Pathway ActivationNrf2 Signaling PathwayNrf2-mediated Cytoprotective SignalingNrf2-mediated ResponsesTherapeutic Resistance Mechanisms

References

55

Cancer statistics, 2018

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2018 · 17K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Colorectal cancer statistics, 2017

Rebecca L. Siegel, Kimberly D. Miller, Stacey A. Fedewa et al. · CA A Cancer Journal for Clinicians · 2017 · 3.9K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform

Daniel R. Rhodes, Jianjun Yu, K. Shanker et al. · Neoplasia · 2004 · 3.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +17

Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology · 2004 · 2.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

Anju Singh, Vikas Misra, Rajesh K. Thimmulappa et al. · PLoS Medicine · 2006 · 1K citations · Full text

Life Sciences, Molecular Biology, Oncology +13