Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Ralph J. DeBerardinis, Anthony Mancuso, Evgueni Daikhin et al. · Proceedings of the National Academy of Sciences · 2007 · 2.5K citations · Full text

Metabolic Remodeling, Cellular Physiology, Protein Synthesis +21

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell et al. · Nature · 2011 · 1.7K citations · Full text

Biochemistry, Redox Regulator, Hypoxia (Medicine) +5

Osteogenesis in transplants of bone marrow cells

A. J. Friedenstein, I. I. Piatetzky-Shapiro, K. V. Petrakova · Development · 1966 · 1.6K citations

Tissue Transplantation, Surgery, Osteoporosis +22

Nutrition Needs of Mammalian Cells in Tissue Culture

Harry Eagle · Science · 1955 · 1.6K citations

Altmetrics, Engineering, Data Science +15

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

Biosynthesis, Essential Role, Biochemistry +9