Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell · 2009 · 4.5K citations · Full text

Life Sciences, Immunology, Microbiology +14

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Seth Rakoff-Nahoum, Justin C. Paglino, Fatima Eslami-Varzaneh et al. · Cell · 2004 · 4.2K citations · Full text

Life Sciences, Immunology, Microbiology +16

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

Noriho Iida, Amiran Dzutsev, Charles A. Stewart et al. · Science · 2013 · 2.2K citations · Full text

Medicine, Immunology, Oncology +17

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14