Concepedia

Scoparone protects neuronal cells from oxygen glucose deprivation/reoxygenation injury

Chunfang Wu, Ting Li, Baihui Zhu, Ruiming Zhu, Youran Zhang, Yong Chen

RSC Advances · 2019 · 13 citations · 11 references

DOIFull text

Open access

Concepts

Abstract

activating Nrf2/HO-1 signaling pathway, suggesting that scoparone might be a potential agent for the ischemic stroke therapy.

References

11

Antioxidant and intestinal anti-inflammatory effects of plant-derived coumarin derivatives

Aline Witaicenis, Leonardo Noboru Seito, Alexandre da Silveira Chagas et al. · Phytomedicine · 2013 · 288 citations

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Staurosporine-Induced Apoptosis of Cultured Rat Hippocampal Neurons Involves Caspase-1-Like Proteases as Upstream Initiators and Increased Production of Superoxide as a Main Downstream Effector

Aaron J. Krohn, Elke Preis, Jochen H.M. Prehn · Journal of Neuroscience · 1998 · 163 citations · Full text

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Ischemic Stroke

Susan A. Randolph · Workplace Health & Safety · 2016 · 117 citations · Full text

, , +10

Scoparone Exerts Anti-Tumor Activity against DU145 Prostate Cancer Cells via Inhibition of STAT3 Activity

Jeong-Kook Kim, Joon-Young Kim, Han-Jong Kim et al. · PLoS ONE · 2013 · 76 citations · Full text

, , +10

β-Caryophyllene Attenuates Focal Cerebral Ischemia-Reperfusion Injury by Nrf2/HO-1 Pathway in Rats

Jie Lou, Guangxiu Cao, Ranran Li et al. · Neurochemical Research · 2016 · 75 citations

, , +12