Concepedia

Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats

Kathryn L. Schwienteck, Kaycee E. Faunce, Kenner C. Rice, Samuel Obeng, Yan Zhang, Bruce E. Blough, Travis W. Grim, S. Stevens Negus, Matthew L. Banks

Neuropharmacology · 2019 · 55 citations · 31 references

DOIFull text

Open access

Concepts

References

31

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 655 citations

, , +17

The Role of Science in Addressing the Opioid Crisis

Nora D. Volkow, Francis S. Collins · New England Journal of Medicine · 2017 · 565 citations · Full text

, , +16

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics

Cullen L. Schmid, Nicole Kennedy, Nicolette C. Ross et al. · Cell · 2017 · 561 citations · Full text

, , +16

Quantifying the Epidemic of Prescription Opioid Overdose Deaths

Puja Seth, Rose A. Rudd, Rita K. Noonan et al. · American Journal of Public Health · 2018 · 438 citations · Full text

, , +11

75 years of opioid research: the exciting but vain quest for the Holy Grail

A.D. Corbett, Graeme Henderson, Alexander T. McKnight et al. · British Journal of Pharmacology · 2006 · 361 citations · Full text

, , +15