Cullen L. Schmid

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics

Cullen L. Schmid, Nicole Kennedy, Nicolette C. Ross et al. · Cell · 2017 · 549 citations · Full text

Opioid Epidemic, Substance Abuse, Health Sciences +14

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Tarsis F. Brust, Jenny Morgenweck, Susy A. Kim et al. · Science Signaling · 2016 · 231 citations · Full text

Pain Disorders, Pain Medicine, Molecular Pain +26

Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions <i>in vivo</i>

Cullen L. Schmid, Kirsten M. Raehal, Laura Bohn · Proceedings of the National Academy of Sciences · 2008 · 223 citations · Full text

Heptahelical Serotonin 2A, Neurotransmitter, Psychopharmacology +21

Serotonin, But Not <i>N</i> -Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex <i>In Vivo</i>

Cullen L. Schmid, Laura Bohn · Journal of Neuroscience · 2010 · 170 citations · Full text

Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

Lei Zhou, Kimberly M. Lovell, Kevin J. Frankowski et al. · Journal of Biological Chemistry · 2013 · 145 citations · Full text

Biochemistry, Functional Selectivity, Medicine +11