The complete synthesis of favipiravir from 2-aminopyrazine

Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model

Sophie J. Smither, Lin Eastaugh, Jackie Steward et al. · Antiviral Research · 2014 · 230 citations

Veterinary Medicine, Infectious Diseases, Toxicology +7

Mechanism of Action of T-705 Ribosyl Triphosphate against Influenza Virus RNA Polymerase

Hidehiro Sangawa, Takashi Komeno, Hiroshi Nishikawa et al. · Antimicrobial Agents and Chemotherapy · 2013 · 191 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)—Sierra Leone, 2014

Changqing Bai, Jinsong Mu, David Kargbo et al. · Clinical Infectious Diseases · 2016 · 159 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacotherapy +16

Role of Human Hypoxanthine Guanine Phosphoribosyltransferase in Activation of the Antiviral Agent T-705 (Favipiravir)

Lieve Naesens, Luke W. Guddat, Dianne T. Keough et al. · Molecular Pharmacology · 2013 · 123 citations

Life Sciences, Biochemistry, Pharmacology +17

Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine <i>C</i>-Nucleosides as Favipiravir (T-705) Analogues

Guangyi Wang, Jinqiao Wan, Yujian Hu et al. · Journal of Medicinal Chemistry · 2016 · 92 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17