Jingshan Shen

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

Wanchao Yin, Chunyou Mao, Xiaodong Luan et al. · Science · 2020 · 1.3K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

Youwen Zhuang, Yue Wang, Bingqing He et al. · Cell · 2022 · 263 citations

Medicine, Medicinal Chemistry, Pharmacology +14

SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

Bingqing Xia, Xu-Rui Shen, Yang He et al. · Cell Research · 2021 · 198 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

Haixia Su, Sheng Yao, Wenfeng Zhao et al. · Nature Communications · 2021 · 196 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

Qing Li, Jianxun Qi, Wei Zhang et al. · Nature Structural & Molecular Biology · 2010 · 167 citations

Life Sciences, Infectious Diseases, Microbiology +8