Concepedia

Publication | Open Access

AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival

DOIFull Paper Access

32

Citations

43

References

2018

Year

Emilio Cosimo, Anuradha Tarafdar, Michael W. Moles, Ailsa K. Holroyd, Natasha Malik, Mark Catherwood, Jodie Hay, Karen Dunn, Alan M. Macdonald, Sylvie M. Guichard,
Clinical Cancer Research

Abstract

Our studies demonstrate that dual mTOR inhibitors show promise as future CLL therapies, particularly in combination with ibrutinib.

References

YearCitations

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