Concepedia

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells

Giulia Stazi, Cecilia Battistelli, Valentina Piano, Roberta Mazzone, Biagina Marrocco, Sara Marchese, Sharon M. Louie, Clemens Zwergel, Lorenzo Antonini, Alexandros Patsilinakos,

European Journal of Medicinal Chemistry · 2018 · 25 citations · 12 references

DOI

Concepts

References

12

Overview of the<i>CCP</i>4 suite and current developments

Martyn Winn, Charles Ballard, Kevin Cowtan et al. · Acta Crystallographica Section D Biological Crystallography · 2011 · 12.4K citations · Full text

Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity

Daniel I. Benjamin, Alyssa J. Cozzo, Xiao‐Dan Ji et al. · Proceedings of the National Academy of Sciences · 2013 · 232 citations · Full text

<i>Thermo</i>FAD, a <i>Thermofluor</i><sup><i>®</i></sup>‐adapted flavin <i>ad hoc</i> detection system for protein folding and ligand binding

Federico Forneris, Roberto Orrù, Daniele Bonivento et al. · FEBS Journal · 2009 · 184 citations · Full text

, , +19

Alkyl and alk-1-enyl ethers of glycerol in lipids from normal and neoplastic human tissues.

Fred H. Snyder, Randall Wood · PubMed · 1969 · 181 citations

, , +16

Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents

Valentina Piano, Daniel I. Benjamin, Sérgio Valente et al. · ACS Chemical Biology · 2015 · 64 citations · Full text

, , +14