Sérgio Valente

TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

Daniela Palacios, Chiara Mozzetta, Silvia Consalvi et al. · Cell stem cell · 2010 · 380 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Claudia Binda, Sérgio Valente, Mauro Romanenghi et al. · Journal of the American Chemical Society · 2010 · 285 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Andrea Galmozzi, Nico Mitro, Alessandra Ferrari et al. · Diabetes · 2012 · 236 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Jay H. Kalin, Muzhou Wu, Andrea V. Gómez et al. · Nature Communications · 2018 · 233 citations · Full text

Medicine, Oncology, Pharmacology +16

Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors

Antonello Mai, Sérgio Valente, Sarah Meade et al. · Journal of Medicinal Chemistry · 2009 · 159 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10