Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Claudia Binda, Sérgio Valente, Mauro Romanenghi, +11

Journal of the American Chemical Society

Drug TargetChromatin StateLsd2 Histone DemethylasesChemical BiologyPharmaceutical Chemistry +14

Histone demethylation catalysed by LSD1 is a flavin‐dependent oxidative process

Federico Forneris, Claudia Binda, Maria A. Vanoni, +2

FEBS Letters

Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation

Federico Forneris, Daniel Ricklin, Jin Wu, +3

Science

D Give InsightProtein AssemblyImmunologyImmune RegulationMolecular Biology +22

A Novel Mammalian Flavin-dependent Histone Demethylase

Aristotele Karytinos, Federico Forneris, Antonella Profumo, +4

Journal of Biological Chemistry

Histone ModificationsEpigenetic ChangeGeneticsGenomic MechanismMolecular Biology +15

Human Histone Demethylase LSD1 Reads the Histone Code

Federico Forneris, Claudia Binda, Maria A. Vanoni, +2

Journal of Biological Chemistry

Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition

Federico Forneris, Claudia Binda, Antonio Adamo, +2

Journal of Biological Chemistry

<i>Thermo</i>FAD, a <i>Thermofluor</i>^<i>®</i>‐adapted flavin <i>ad hoc</i> detection system for protein folding and ligand binding

Federico Forneris, Roberto Orrù, Daniele Bonivento, +2

FEBS Journal

Protein AssemblyMolecular BiologyLigand BindingAnalytical UltracentrifugationProtein Refolding +17

Multiple pathways guide oxygen diffusion into flavoenzyme active sites

Riccardo Baron, Conor T. Riley, Pirom Chenprakhon, +9

Proceedings of the National Academy of Sciences

Local EnvironmentBiochemistrySpontaneous Protein-guided OProtein FoldingBiocatalysis +11

Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System

Cristina Zibetti, Antonio Adamo, Claudia Binda, +7

Journal of Neuroscience

Lsd1 TranscriptEpigenetic ChangeGeneticsLsd1 Splice VariantsSynaptic Signaling +18

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9

Michael A. Hadders, Doryen Bubeck, Pietro Roversi, +7

Cell Reports

Membrane StructureProteinlipid InteractionBiochemistryNatural SciencesMolecular Biology +4