Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II

Reva C. Lawrence, David T. Felson, Charles G. Helmick et al. · Arthritis & Rheumatism · 2007 · 5.5K citations

Medicine, Internal Medicine, Epidemiology +9

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li et al. · Genes & Development · 2007 · 3.2K citations · Full text

Life Sciences, Cell Biology, Genetics +17

The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

Jianbin Huang, Shian Wu, Jose Barrera et al. · Cell · 2005 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.

Peter G. Mitchell, Holly A. Magna, Lucy Reeves et al. · Journal of Clinical Investigation · 1996 · 943 citations · Full text

Medicine, Pathology, Carcinogenesis +15

Akt Phosphorylates the Yes-Associated Protein, YAP, to Induce Interaction with 14-3-3 and Attenuation of p73-Mediated Apoptosis

Subham Basu, Nicholas F. Totty, Meredith S. Irwin et al. · Molecular Cell · 2003 · 839 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13