EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation

Jong-Ho Lee, Rui Liu, Jing Li, +16

Molecular Cell

ThrombopoiesisSignal TransductionCell SignalingReceptor Tyrosine KinaseProtein Phosphorylation +6

Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets

Rui Liu, Jingyi Li, Rilei Yu, +7

Molecular Cell

Signal TransductionBiochemistryNatural SciencesCholine KinaseAutophagy +9

FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer

Rui Liu, Jingyi Li, Ke Xie, +11

Cancer Research

Tumor BiologyEpigenetic RegulationOther FgfrsMedicineColorectal Cancer +13

Cholesterol Esterification Inhibition Suppresses Prostate Cancer Metastasis by Impairing the Wnt/β-catenin Pathway

Hyeon Jeong Lee, Jie Li, Renee E. Vickman, +8

Molecular Cancer Research

Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development

Yong Gong, Songjian Li, Rui Liu, +5

Journal of Molecular Medicine

InflammationMusculoskeletal ResearchBone Morphogenic ProteinCartilage DegenerationOsteoarthritis +5

Mechanism of Cancer Cell Adaptation to Metabolic Stress

Rui Liu, Zhenjun Li, Shujun Bai, +8

Molecular & Cellular Proteomics

PathologyMetabolic RemodelingGastric TumorsTumor BiologyMetabolic Reprogramming +16

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1

Rui Liu, Shan Huang, Yunlong Lei, +8

Oncotarget

Colorectal Cancer GrowthOncologyMedicinePathologyColorectal Cancer +10

Phosphofructokinase 1 Platelet Isoform Promotes β-Catenin Transactivation for Tumor Development

Jong-Ho Lee, Fei Shao, Jinjie Ling, +10

Frontiers in Oncology

Oxygen-sensitive methylation of ULK1 is required for hypoxia-induced autophagy

Jingyi Li, Tao Zhang, Tao Ren, +7

Nature Communications

CDK7-YAP-LDHD axis promotes D-lactate elimination and ferroptosis defense to support cancer stem cell-like properties

Mengzhu Lv, Ying Gong, Xuesong Liu, +13

Signal Transduction and Targeted Therapy