Dong Guo

Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα

Dong Guo, Yingying Tong, Xiaoming Jiang et al. · Cell Metabolism · 2022 · 415 citations · Full text

Medicine, Cancer Biology, Oncology +16

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

Rongxuan Zhu, Xianglai Ye, Xiaotong Lu et al. · Cell Metabolism · 2024 · 223 citations

Medicine, Molecular Biology, Oncology +15

SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells

Yingying Tong, Dong Guo, Shuhai Lin et al. · Molecular Cell · 2021 · 203 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding

Wei Wang, Fei Shao, Xueying Yang et al. · Nature Communications · 2021 · 193 citations · Full text

Life Sciences, Genetics, Oncology +17

WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis

Xueying Yang, Fei Shao, Dong Guo et al. · Cell Death and Disease · 2021 · 172 citations · Full text

Life Sciences, Molecular Biology, Oncology +17