Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα

Dong Guo, Yingying Tong, Xiaoming Jiang, +13

Cell Metabolism

Tumor BiologyImmune EvasionAerobic Glycolysis PromotesCancer ImmunosurveillanceCell Regulation +11

SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells

Yingying Tong, Dong Guo, Shuhai Lin, +11

Molecular Cell

Gls SuccinylationTumor BiologySignal TransductionCell RegulationBiochemistry +9

KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells

Yingying Tong, Dong Guo, Yan Dong, +9

Cancer Letters

Tumor BiologySignal TransductionSignaling PathwayPancreatic CancerActivity-mediated 14-3-3ζ Upregulation +10

Arsenic sulfide as a potential anti-cancer drug

Wenping Ding, Lian Zhang, Sungkyoung Kim, +5

Molecular Medicine Reports

Chemoprevention StrategyCell DeathCancer BiologyTumor BiologyMedicinal Chemistry +15

Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo

Siyu Chen, Wei Tian, Lian Zhang, +3

Drug Design Development and Therapy

Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth

Siyu Chen, Lian Zhang, Yingying Tong, +2

Drug Design Development and Therapy

Arsenic sulfide inhibits cell migration and invasion of gastric cancer in vitro and in vivo

Siyu Chen, Lian Zhang, Sungkyoung Kim, +4

Drug Design Development and Therapy

Study of Arsenic Sulfide in Solid Tumor Cells Reveals Regulation of Nuclear Factors of Activated T-cells by PML and p53

Wenping Ding, Yingying Tong, Xiuli Zhang, +2

Scientific Reports

Chemoprevention StrategyT-regulatory CellImmunologyP53 Responsive ElementsTumor Biology +15

NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide

Xiuli Zhang, Ting Kang, Lian Zhang, +3

Oncotarget

Nerve growth factor prevents arsenic‐induced toxicity in PC12 cells through the AKT/GSK‐3β/NFAT pathway

Zhen Tan, Ting Kang, Xiuli Zhang, +2

Journal of Cellular Physiology

ApoptosisImmunologyCell DeathPeripheral NervesPotential Risk +22