Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors <i>In Vitro</i> and <i>In Vivo</i> - Concepedia

Concepedia

Publication | Open Access

Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors <i>In Vitro</i> and <i>In Vivo</i>

DOI Full Paper Access

75

Citations

33

References

2018

Year

Gerhard Siemeister, Anne Mengel, Amaury E. Fernández‐Montalván, Wilhelm Bone, Jens Schröder, Sabine Zitzmann-Kolbe, Hans Briem, Stefan Prechtl, Simon J. Holton, Ursula Mönning,

Clinical Cancer Research

Abstract

Our findings suggest clinical proof-of-concept studies evaluating BAY 1816032 in combination with taxanes or PARP inhibitors to enhance their efficacy and potentially overcome resistance.

References

	Year	Citations

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