Concepedia

Simon J. Holton

SJ

27

Publications

1.3K

Citations

20

H-Index

1964

Active since

Affiliations

Bayer (Germany)(Current)

European Molecular Biology Laboratory

University of Oxford

Centre National de la Recherche Scientifique

Mansfield University

Simon J. Holton is an author at Bayer (Germany) specializing in medicine, biochemistry, and molecular biology.

Top concepts

MedicineBiochemistryMolecular BiologyNatural SciencesMicrobiologyPharmacologyStructural BiologySignal TransductionCell SignalingMolecular Pharmacology

Publications per year

1964–2022

27

Publications

27

WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern

Christian Poulsen, Santosh Panjikar, Simon J. Holton et al. · PLoS ONE · 2014 · 113 citations · Full text

Sequence Motif, Homodimeric Precursor, Structural Bioinformatics +13

Structures of P. falciparum PfPK5 Test the CDK Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition

Simon J. Holton, Anaïs Merckx, Darren J. Burgess et al. · Structure · 2003 · 95 citations · Full text

Protein Function, Signal Transduction, Biochemistry +12

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

Amaury E. Fernández‐Montalván, Markus Berger, Benno Kuropka et al. · ACS Chemical Biology · 2017 · 88 citations · Full text

Atad2 Bromodomain Dimerization, Epigenetic Change, Genetics +20

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

Seong Joo Koo, Amaury E. Fernández‐Montalván, Volker Badock et al. · Oncotarget · 2016 · 87 citations · Full text

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer

Sebastian M. Dieter, Christine Siegl, Paula Codó et al. · Cell Reports · 2021 · 85 citations · Full text

Tumor Biology, Oncology, Chemoprevention Strategy +7

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