Concepedia
Statistics
Publications
27
Citations
1.3K
H-Index
20
Active since
1964
Affiliations
Bayer (Germany)(Current)
European Molecular Biology Laboratory
University of Oxford
Centre National de la Recherche Scientifique
Mansfield University
Simon J. Holton is an author at Bayer (Germany) specializing in medicine, biochemistry, and molecular biology.
Top concepts
MedicineBiochemistryMolecular BiologyNatural SciencesMicrobiologyPharmacologyStructural BiologySignal TransductionCell SignalingMolecular Pharmacology
Publications per year
1964–2022
WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern
Christian Poulsen, Santosh Panjikar, Simon J. Holton et al. · PLoS ONE · 2014 · 113 citations · Full text
Sequence Motif, Homodimeric Precursor, Structural Bioinformatics +13
Structures of P. falciparum PfPK5 Test the CDK Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Simon J. Holton, Anaïs Merckx, Darren J. Burgess et al. · Structure · 2003 · 95 citations · Full text
Protein Function, Signal Transduction, Biochemistry +12
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E. Fernández‐Montalván, Markus Berger, Benno Kuropka et al. · ACS Chemical Biology · 2017 · 88 citations · Full text
Atad2 Bromodomain Dimerization, Epigenetic Change, Genetics +20
ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication
Seong Joo Koo, Amaury E. Fernández‐Montalván, Volker Badock et al. · Oncotarget · 2016 · 87 citations · Full text
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
Sebastian M. Dieter, Christine Siegl, Paula Codó et al. · Cell Reports · 2021 · 85 citations · Full text
Tumor Biology, Oncology, Chemoprevention Strategy +7
1–5 of 27