Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

C. Marcela Díaz‐Montero, Mohamed L. Salem, Michael I. Nishimura et al. · Cancer Immunology Immunotherapy · 2008 · 1.2K citations

Medicine, Cancer Biology, Oncology +17

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C

Bruno Sangro, Carlos Gómez-Martín, Manuel de la Mata et al. · Journal of Hepatology · 2013 · 988 citations

Medicine, Oncology, Pharmacology +15

Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial

Tadatoshi Takayama, Teruaki Sekine, Masatoshi Makuuchi et al. · The Lancet · 2000 · 848 citations

Medicine, Immunology, Oncology +10

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species

Sergei Kusmartsev, Yulia Nefedova, Daniel Yoder et al. · The Journal of Immunology · 2004 · 838 citations

Medicine, Immunology, Oncology +17

Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma

Austin G. Duffy, Susanna V. Ulahannan, Oxana Makorova-Rusher et al. · Journal of Hepatology · 2016 · 818 citations

Medicine, Oncology, Surgery +12