Concepedia

Myeloid-derived Suppressor Cell Function

Myeloid-Derived Suppressor Cell Function is a biological regulatory mechanism, within the broader class of immune cell functions, distinguished by the capacity of myeloid-derived suppressor cells to inhibit T-cell activation and proliferation in the tumor microenvironment, thereby modulating cancer immunosurveillance.

1.5K

Publications

140K

Citations

9.8K

Authors

1.8K

Institutions

Publications per year

2017–2026

695

Parents

Publications

1.5K

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

Bo Huang, Ping‐Ying Pan, Qingsheng Li et al. · Cancer Research · 2006 · 1.4K citations

, , +17

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell–Dependent Antitumor Immunity

Julie Vincent, Grégoire Mignot, Fanny Chalmin et al. · Cancer Research · 2010 · 1.2K citations

, , +17

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

C. Marcela Díaz‐Montero, Mohamed L. Salem, Michael I. Nishimura et al. · Cancer Immunology Immunotherapy · 2008 · 1.2K citations

, , +17

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

Cesar A. Corzo, Thomas Condamine, Lily Lu et al. · The Journal of Experimental Medicine · 2010 · 1.1K citations · Full text

, , +17

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

Yang Li, Laura M. DeBusk, Koari Fukuda et al. · Cancer Cell · 2004 · 1.1K citations · Full text

, , +16

1–5 of 1.5K

Authors

9.8K

  1. DI
    Dmitry I. Gabrilovich

    Moffitt Cancer Center, United States

    29 publications · 8.2K citations

    28

    h-index

  2. SO
    Suzanne Ostrand‐Rosenberg

    University of Maryland, Baltimore County, United States

    23 publications · 6.8K citations

    21

    h-index

  3. VB
    Vincenzo Bronte

    University of Verona, Italy

    21 publications · 3.6K citations

    19

    h-index

  4. HX
    Huaxi Xu

    Jiangsu University, China

    16 publications · 1.1K citations

    16

    h-index

  5. JZ
    Jie Zhou

    Sun Yat-sen University, China

    16 publications · 1.3K citations

    15

    h-index

1–5 of 9.8K

Institutions

1.8K

  1. Sun Yat-sen University

    Guangzhou, China

    38 h-index

    378 publications

    32.2K citations

  2. Moffitt Cancer Center

    Tampa, United States

    33 h-index

    224 publications

    57.1K citations

  3. National Cancer Institute

    Bethesda, United States

    31 h-index

    206 publications

    21.9K citations

  4. Inserm

    Paris, France

    29 h-index

    197 publications

    54.5K citations

  5. Roswell Park Comprehensive Cancer Center

    Buffalo, United States

    24 h-index

    140 publications

    12.2K citations

  6. National Institutes of Health

    Bethesda, United States

    23 h-index

    133 publications

    13.9K citations

  7. University of Maryland, Baltimore County

    Baltimore, United States

    22 h-index

    79 publications

    26.9K citations

  8. Fudan University

    Shanghai, China

    22 h-index

    157 publications

    8.6K citations

1–8 of 1.8K

Venues

  1. The Journal of Immunology

    JI · 89 publications · 14.7K citations

    63

    h-index

  2. Cancer Research

    61 publications · 17.2K citations

    52

    h-index

  3. OncoImmunology

    74 publications · 4.5K citations

    39

    h-index

  4. Cancer Immunology Immunotherapy

    55 publications · 6.1K citations

    37

    h-index

  5. Frontiers in Immunology

    60 publications · 3K citations

    33

    h-index

1–5