Concepedia

The nucleosome remodeling and deacetylase complex protein CHD4 regulates neural differentiation of mouse embryonic stem cells by down-regulating p53

Akira Hirota, May Nakajima‐Koyama, Yuhei Ashida, Eisuke Nishida

Journal of Biological Chemistry · 2018 · 20 citations · 39 references

DOIFull text

Open access

Concepts

Abstract

knockdown. Our findings reveal that the CHD4/NuRD complex regulates neural differentiation of ESCs by down-regulating p53.

References

39

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

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NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities

Yutong Xue, Jiemin Wong, G. Tony Moreno et al. · Molecular Cell · 1998 · 985 citations · Full text

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Vertebrate neurogenesis is counteracted by Sox1–3 activity

Magdalena Bylund, Elisabet Andersson, Bennett G. Novitch et al. · Nature Neuroscience · 2003 · 836 citations

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The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

Yi Zhang, Gary LeRoy, Hans-Peter Seelig et al. · Cell · 1998 · 818 citations · Full text

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MDM2–HDAC1‐mediated deacetylation of p53 is required for its degradation

Akihiro Ito, Yoshiharu Kawaguchi, Chun-Hsiang Lai et al. · The EMBO Journal · 2002 · 566 citations · Full text

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