Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

Maria Björkqvist, Edward J. Wild, Jenny Thiele et al. · The Journal of Experimental Medicine · 2008 · 641 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Early and Progressive Accumulation of Reactive Microglia in the Huntington Disease Brain

Ellen Sapp, Kimberly B. Kegel, Neil Aronin et al. · Journal of Neuropathology & Experimental Neurology · 2001 · 540 citations · Full text

Life Sciences, Neurology, Neuroscience +15

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

Daniel Zwilling, Shaoyi Huang, Korrapati V. Sathyasaikumar et al. · Cell · 2011 · 514 citations · Full text

Life Sciences, Neuroscience, Pharmacology +10

Microglial activation correlates with severity in Huntington disease

Nicola Pavese, Alexander Gerhard, Yen Tai et al. · Neurology · 2006 · 459 citations

Life Sciences, Neurology, Neuroscience +17

Microglial activation in presymptomatic Huntington's disease gene carriers

Yen Tai, Nicola Pavese, Alexander Gerhard et al. · Brain · 2007 · 434 citations · Full text

Life Sciences, Neurology, Neuroscience +17