The use of PBPK modeling across the pediatric age range using propofol as a case

Prediction of the Clearance of Eleven Drugs and Associated Variability in Neonates, Infants and Children

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Drug Safety, Pharmacoepidemiology, Pharmacology +8

Population Pharmacokinetics of Propofol

J. Schüttler, Harald Ihmsen · Anesthesiology · 2000 · 435 citations · Full text

A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 419 citations

Pharmacokinetic Modeling, Pharmacodynamics, Pharmacological Study +9

Mechanistic Approaches to Volume of Distribution Predictions: Understanding the Processes

Trudy Rodgers, Malcolm Rowland · Pharmaceutical Research · 2007 · 409 citations

Probabilistic Forecasting, Engineering, Density Estimation +12

CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants

L M Hesse, Karthik Venkatakrishnan, Michael H. Court et al. · Drug Metabolism and Disposition · 2000 · 397 citations