Concepedia

The CCT chaperonin is a novel regulator of Ca <sup>2+</sup> signaling through modulation of Orai1 trafficking

Rawad Hodeify, Manjula Nandakumar, Maryam Own, Raphaël Courjaret, Johannes Graumann, Satanay Hubrack, Khaled Machaca

Science Advances · 2018 · 23 citations · 42 references

DOIFull text

Open access

Concepts

Abstract

A chaperone complex (CCT) regulates the trafficking of a calcium channel (Orai1) and, as such, modulates cellular function.

References

42

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Jürgen Cox, Matthias Mann · Nature Biotechnology · 2008 · 15.7K citations

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In-gel digestion for mass spectrometric characterization of proteins and proteomes

Andrej Shevchenko, Henrik Tomas, J. Havli et al. · Nature Protocols · 2006 · 5.1K citations

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Predicting Coiled Coils from Protein Sequences

Andrei N. Lupas, Marc Van Dyke, Jeff Stock · Science · 1991 · 4K citations

, , +15

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

, , +12

STIM1, an essential and conserved component of store-operated Ca2 <b>+</b> channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin et al. · The Journal of Cell Biology · 2005 · 1.8K citations · Full text

, , +17