Concepedia

The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices

Dimakatso Alice Senthebane, Tina Jonker, Arielle Rowe, Nicholas Ekow Thomford, Daniella Munro, Collet Dandara, Ambroise Wonkam, Dhirendra Govender, Bridget Calder, Nelson C. Soares,

International Journal of Molecular Sciences · 2018 · 134 citations · 144 references

DOIFull text

Open access

Abstract

Our study shows that ECM proteins play a key role in the response of cancer cells to chemotherapy and suggest that targeting ECM proteins can be an effective therapeutic strategy against chemoresistant tumors.

References

144

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.5K citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

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Universal sample preparation method for proteome analysis

Jacek R. Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj et al. · Nature Methods · 2009 · 8.5K citations

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