Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Hsiuchen Chen, Scott A. Detmer, Andrew J. Ewald et al. · The Journal of Cell Biology · 2003 · 2.5K citations · Full text

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Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

Hsiuchen Chen, Marc Vermulst, Yun E. Wang et al. · Cell · 2010 · 1.2K citations · Full text

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Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

Maria Mańczak, Thimmappa S. Anekonda, Edward Henson et al. · Human Molecular Genetics · 2006 · 1.1K citations · Full text

Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

Nagalingam R. Sundaresan, Madhu Gupta, Gene Kim et al. · Journal of Clinical Investigation · 2009 · 982 citations · Full text

Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell

Luciano Conti, Steven M. Pollard, Thorsten Gorba et al. · PLoS Biology · 2005 · 868 citations · Full text

Regenerative Medicine, Neuroregeneration, Developmental Biology +13