Publication | Open Access

Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor

Medicinal ChemistryBiochemistryMedicineNatural SciencesReceptor Tyrosine KinaseRational Drug DesignAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery