Jiaxin Wu

Surface Iron Species in Palladium–Iron Intermetallic Nanocrystals that Promote and Stabilize CO₂ Methanation

Laihao Luo, Menglin Wang, Yi Cui et al. · Angewandte Chemie International Edition · 2020 · 79 citations

Berberine Damages the Cell Surface of Methicillin-Resistant Staphylococcus aureus

Xiujuan Zhang, Xiaoying Sun, Jiaxin Wu et al. · Frontiers in Microbiology · 2020 · 63 citations · Full text

Discovery of N -(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC

Yongfei Chen, Jiaxin Wu, Aoli Wang et al. · European Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

Drug Target, Medicine, Rational Drug Design +7

Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor

Beilei Wang, Jiaxin Wu, Yun Wu et al. · European Journal of Medicinal Chemistry · 2018 · 50 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells

Hong Wu, Aoli Wang, Wei Zhang et al. · Oncotarget · 2015 · 46 citations · Full text

Novel Therapy, Medicine, Receptor Tyrosine Kinase +14