Zongru Jiang

Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor

Beilei Wang, Jiaxin Wu, Yun Wu et al. · European Journal of Medicinal Chemistry · 2018 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52

Wenliang Wang, Zongru Jiang, Chen Hu et al. · Acta Pharmacologica Sinica · 2020 · 46 citations · Full text

Medicine, Oncology, Pharmacology +9

Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies

Husheng Mei, Hong Wu, Jing Yang et al. · Signal Transduction and Targeted Therapy · 2023 · 45 citations · Full text

Medicine, Molecular Biology, Oncology +11

Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent

Zongru Jiang, Li Wang, Xuesong Liu et al. · Acta Pharmaceutica Sinica B · 2019 · 36 citations · Full text

Medicine, Oncology, Pharmacology +16

T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway

Lijuan Wan, Lingli Gong, Wei Wang et al. · Parasites & Vectors · 2015 · 34 citations · Full text

Life Sciences, Neuroscience, Pathobiology +17