Concepedia

Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

Payam A. Gammage, Carlo Viscomi, Marie‐Lune Simard, Ana S.H. Costa, Edoardo Gaude, Christopher A. Powell, Lindsey Van Haute, Beverly J. McCann, Pedro Rebelo‐Guiomar, Raffaele Cerutti,

Nature Medicine · 2018 · 305 citations · 25 references

DOI

Concepts

References

25

Mitochondrial DNA Mutation Associated with Leber's Hereditary Optic Neuropathy

Douglas C. Wallace, Gurparkash Singh, Marie T. Lott et al. · Science · 1988 · 2.4K citations

, , +17

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

Ian Holt, A. E. Harding, J A Morgan-Hughes · Nature · 1988 · 1.8K citations

, , +14

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

, , +12

Prevalence of nuclear and mitochondrial <scp>DNA</scp> mutations related to adult mitochondrial disease

Gráinne S. Gorman, Andrew M. Schaefer, Yi Shiau Ng et al. · Annals of Neurology · 2015 · 943 citations · Full text

, , +13

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

Lyndsey Craven, Helen Tuppen, Gareth D. Greggains et al. · Nature · 2010 · 480 citations · Full text

, , +10