Concepedia

Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease

Michael D. Barker, John Liddle, Francis Atkinson, David M. Wilson, Marion C. Dickson, César Ramírez-Molina, Huw D. Lewis, Rob P. Davis, D.O. Somers, Margarete Neu,

Bioorganic & Medicinal Chemistry Letters · 2018 · 22 citations · 7 references

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References

7

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

Bruce N. Ames, Frank D. Lee, William E. Durston · Proceedings of the National Academy of Sciences · 1973 · 1.5K citations · Full text

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An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

Michael E. Weinblatt, Arthur Kavanaugh, Mark C. Genovese et al. · New England Journal of Medicine · 2010 · 377 citations

, , +15

Treatment of rheumatoid arthritis with a syk kinase inhibitor: A twelve‐week, randomized, placebo‐controlled trial

Michael E. Weinblatt, Arthur Kavanaugh, Rubén Burgos‐Vargas et al. · Arthritis & Rheumatism · 2008 · 336 citations

, , +12

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment

Eli O. Meltzer, Robert Berkowitz, Elliott B. Grossbard · Journal of Allergy and Clinical Immunology · 2005 · 149 citations

, , +16

Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor

John Liddle, Francis Atkinson, Michael D. Barker et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 54 citations · Full text

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