David M. Wilson

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 958 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis, John Liddle, Jim Coote et al. · Nature Chemical Biology · 2015 · 760 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +2

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral, Small-Molecule Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor AZD6244 (ARRY-142886) in Patients With Advanced Cancers

Alex A. Adjei, Roger B. Cohen, Wilbur A. Franklin et al. · Journal of Clinical Oncology · 2008 · 573 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Adriana E. Tron, Matthew A. Belmonte, Ammar Adam et al. · Nature Communications · 2018 · 486 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

Rahul S. Desikan, Chun Chieh Fan, Yunpeng Wang et al. · PLoS Medicine · 2017 · 410 citations · Full text

Life Sciences, Genetics, Neurology +17