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Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1

Neurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseAutophagyCell DeathApp/ps1 Transgenic MiceDegenerative PathologySphingomyelin Synthase 1NeurologyNeurodegenerationLysosomal DegradationBrain PathologyMedicineCell BiologyNeuroinflammation