De-En Xu

Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model

Mei‐Hong Lu, Wen‐Li Ji, Hong Chen et al. · Frontiers in Aging Neuroscience · 2021 · 70 citations · Full text

Cerebral Organoid, Therapeutics, Social Sciences +28

Clemastine Ameliorates Myelin Deficits via Preventing Senescence of Oligodendrocytes Precursor Cells in Alzheimer’s Disease Model Mouse

Yuanyuan Xie, Tingting Pan, De-En Xu et al. · Frontiers in Cell and Developmental Biology · 2021 · 57 citations · Full text

Amyloid precursor protein at node of Ranvier modulates nodal formation

De-En Xu, Wen-Min Zhang, Zara Zhuyun Yang et al. · Cell Adhesion & Migration · 2014 · 40 citations · Full text

Alzheimer's Disease, App Ko, Protein Folding +12

Reducing Nav1.6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription

De‐Juan Yuan, Guang Yang, Wei Wu et al. · Aging Cell · 2022 · 33 citations · Full text

Synaptic Transmission, Rescue Cognitive Deficits, Molecular Biology +28

Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy

Zhenyu Li, Lihua Chen, Xiu‐Yun Zhao et al. · Experimental Neurology · 2021 · 29 citations

Ad Model Mouse, Cell Autophagy, Mitophagy +9