CX-5461-loaded nucleolus-targeting nanoplatform for cancer therapy through induction of pro-death autophagy

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

Denis Drygin, Amy Lin, Josh Bliesath et al. · Cancer Research · 2010 · 621 citations

Life Sciences, Medicinal Chemistry, Oncology +17

pH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids

Faheem Muhammad, Mingyi Guo, Wenxiu Qi et al. · Journal of the American Chemical Society · 2011 · 602 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij et al. · Cancer Cell · 2012 · 560 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Multifunctional Envelope-Type Mesoporous Silica Nanoparticles for Tumor-Triggered Targeting Drug Delivery

Jing Zhang, Zhefan Yuan, Ya Wang et al. · Journal of the American Chemical Society · 2013 · 516 citations

Pharmacy, Oncology, Pharmaceutics +17

pH-Responsive Nanogated Ensemble Based on Gold-Capped Mesoporous Silica through an Acid-Labile Acetal Linker

Rui Liu, Ying Zhang, Xiang Zhao et al. · Journal of the American Chemical Society · 2010 · 390 citations

Natural Sciences, Chemistry, Materials Science +17