Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Siân Jones, D. Williams Parsons, Jimmy Lin et al. · Science · 2008 · 4K citations · Full text

Engineering, Genetics, Pathology +17

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Kandice R. Levental, Hongmei Yu, Laura Kass et al. · Cell · 2009 · 4K citations · Full text

Enhancing Integrin, Medicine, Cell-matrix Interaction +7

Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer

Patrick Hermann, Stephan Huber, Tanja Herrler et al. · Cell stem cell · 2007 · 2.9K citations · Full text

Metastatic Activity, Pancreatic Cancer, Medicine +12

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Paolo P. Provenzano, Kevin W. Eliceiri, Jay M. Campbell et al. · BMC Medicine · 2006 · 1.8K citations · Full text

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Michele Zanoni, Filippo Piccinini, Chiara Arienti et al. · Scientific Reports · 2016 · 1.1K citations · Full text