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Publication | Open Access

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy

DOIFull Paper Access

18

Citations

39

References

2018

Year

Gabriela Canalli Kretzschmar, Luana Caroline Oliveira, Renato Nisihara, Thirumalaisamy P. Velavan, Sérvio Túlio Stinghen, Ewalda R. S. Stahlke, Maria Luiza Petzl‐Erler, Iara Messias-Reason, Angelica Beate Winter Boldt
PLoS neglected tropical diseases

Abstract

The results lead us to suggest a regulatory role for CR1 polymorphisms on mRNA and sCR1 levels, with haplotype-specific effects increasing susceptibility to leprosy, probably by enhancing parasite phagocytosis and inflammation.

References

YearCitations

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