Complement Gene Variants

Complement Gene Variants is a genetic construct referring to inherited or acquired alterations in the DNA sequences of genes encoding components of the complement system, distinguished by their functional impact on complement activation, regulation, and associated immunological outcomes.

424

Publications

25.3K

Citations

2.9K

Authors

850

Institutions

Publications per year

2017–2026

Variants

Complement Genetic Variants

Parents

Complement Regulation

Publications

424

A common haplotype in the complement regulatory gene factor H ( <i>HF1/CFH</i> ) predisposes individuals to age-related macular degeneration

Gregory S. Hageman, Don H. Anderson, Lincoln V. Johnson et al. · Proceedings of the National Academy of Sciences · 2005 · 2K citations · Full text

Medicine, Genetics, Molecular Genetics +17

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text

Life Sciences, Genetics, Human Genetics +13

<i>HTRA1</i> Promoter Polymorphism in Wet Age-Related Macular Degeneration

Andrew T. DeWan, Mugen Liu, Stephen E. Hartman et al. · Science · 2006 · 876 citations

Life Sciences, Genetics, Molecular Genetics +17

Complement C3 Variant and the Risk of Age-Related Macular Degeneration

John R.W. Yates, Tiina Sepp, Baljinder K. Matharu et al. · New England Journal of Medicine · 2007 · 828 citations · Full text

Medicine, Genetics, Ophthalmology +17

Inherited structural polymorphism of the fourth component of human complement.

Z Awdeh, C A Alper · Proceedings of the National Academy of Sciences · 1980 · 486 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

1–5 of 424

Authors

2.9K

CY
C. Yung Yu
The Ohio State University, United States
18 publications · 1.8K citations
17
h-index
VF
Véronique Frémeaux‐Bacchi
Hôpital Européen Georges-Pompidou, France
16 publications · 1.8K citations
16
h-index
AI
Anneke I. den Hollander
Radboud University Nijmegen, Netherlands
15 publications · 581 citations
14
h-index
CB
Carel B. Hoyng
Radboud University Nijmegen, Netherlands
13 publications · 528 citations
13
h-index
BZ
Bi Zhou
The Ohio State University, United States
12 publications · 1.1K citations
12
h-index

1–5 of 2.9K

Institutions

850

1–8 of 850

Venues

The Journal of Immunology
JI · 19 publications · 943 citations
16
h-index
Investigative Ophthalmology & Visual Science
IOVS · 16 publications · 766 citations
15
h-index
Human Genetics
15 publications · 417 citations
14
h-index
Immunogenetics
14 publications · 589 citations
13
h-index
PubMed
Repository · 16 publications · 396 citations
13
h-index

1–5