Concepedia

Complement System Genes

Complement System Genes is a genetic construct that belongs to the class of immune-related gene families and specifically comprises genes encoding proteins involved in the complement cascade, a critical component of innate immunity that enhances pathogen clearance and modulates adaptive immune responses.

1.2K

Publications

64.5K

Citations

5.8K

Authors

1.5K

Institutions

Publications per year

2017–2026

171

Parents

Publications

1.2K

Genetics and Outcome of Atypical Hemolytic Uremic Syndrome

Véronique Frémeaux‐Bacchi, Fádi Fakhouri, Arnaud Garnier et al. · Clinical Journal of the American Society of Nephrology · 2013 · 713 citations

, , +16

The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

Lawrence Shapiro, Philipp E. Scherer · Current Biology · 1998 · 656 citations · Full text

, , +12

Inherited structural polymorphism of the fourth component of human complement.

Z Awdeh, C A Alper · Proceedings of the National Academy of Sciences · 1980 · 486 citations · Full text

, , +17

Gene Copy-Number Variation and Associated Polymorphisms of Complement Component C4 in Human Systemic Lupus Erythematosus (SLE): Low Copy Number Is a Risk Factor for and High Copy Number Is a Protective Factor against SLE Susceptibility in European Americans

Yan Yang, Erwin K. Chung, Yee Ling Wu et al. · The American Journal of Human Genetics · 2007 · 468 citations · Full text

, , +17

Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome

Elena Goicoechea de Jorge, Claire L. Harris, Jorge Esparza-Gordillo et al. · Proceedings of the National Academy of Sciences · 2006 · 445 citations · Full text

, , +16

1–5 of 1.2K

Authors

5.8K

  1. SR
    Santiago Rodrı́guez de Córdoba

    Centro de Investigaciones Biológicas Margarita Salas, Spain

    29 publications · 2.7K citations

    25

    h-index

  2. CY
    C. Yung Yu

    The Ohio State University, United States

    23 publications · 2.6K citations

    21

    h-index

  3. HR
    Harvey R. Colten

    Harvard University, United States

    22 publications · 1.7K citations

    18

    h-index

  4. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    18 publications · 1.3K citations

    17

    h-index

  5. VF
    Véronique Frémeaux‐Bacchi

    Hôpital Européen Georges-Pompidou, France

    16 publications · 2.8K citations

    16

    h-index

1–5 of 5.8K

Institutions

1.5K

  1. Washington University in St. Louis

    St Louis, United States

    33 h-index

    214 publications

    15.9K citations

  2. University of Oxford

    Oxford, United Kingdom

    29 h-index

    111 publications

    12.2K citations

  3. Harvard University

    Cambridge, United States

    24 h-index

    116 publications

    9.1K citations

  4. University of Pennsylvania

    Philadelphia, United States

    22 h-index

    63 publications

    4.4K citations

  5. Inserm

    Paris, France

    21 h-index

    96 publications

    4.1K citations

  6. Johannes Gutenberg University Mainz

    Mainz, Germany

    20 h-index

    87 publications

    3.8K citations

  7. Radboud University Nijmegen

    Nijmegen, The Netherlands

    19 h-index

    102 publications

    4.7K citations

  8. Centro de Investigaciones Biológicas Margarita Salas

    Madrid, Spain

    19 h-index

    61 publications

    5.6K citations

1–8 of 1.5K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 54 publications · 7.7K citations

    46

    h-index

  2. The Journal of Immunology

    JI · 94 publications · 5.2K citations

    44

    h-index

  3. Journal of Biological Chemistry

    JBC · 34 publications · 2.5K citations

    29

    h-index

  4. Immunogenetics

    45 publications · 1.8K citations

    25

    h-index

  5. PubMed

    Repository · 59 publications · 2.1K citations

    24

    h-index

1–5