Concepedia

Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo

Wenbo Zhang, Chao Huang, Aijun Sun, Liang Qiao, Xi Zhang, Junlong Huang, Xuejun Sun, Xiangqun Yang, Shanquan Sun

Biomedicine & Pharmacotherapy · 2018 · 34 citations · 22 references

DOI

Concepts

References

22

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi et al. · Nature Medicine · 2007 · 2.5K citations

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Telomere dysfunction induces metabolic and mitochondrial compromise

Ergün Sahin, Simona Colla, Marc Liesa et al. · Nature · 2011 · 1.3K citations

, , +14

Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies

Alexandra Stolzing, Elena Jones, Dennis McGonagle et al. · Mechanisms of Ageing and Development · 2007 · 1.2K citations · Full text

, , +14

Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts

Gretchen H. Stein, Linda F. Drullinger, Alexandre Soulard et al. · Molecular and Cellular Biology · 1999 · 849 citations · Full text

, , +17

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Mark Pearson, Roberta Carbone, Carla Sebastiani et al. · Nature · 2000 · 832 citations

, , +16