Concepedia

Development of novel 2,4-bispyridyl thiophene–based compounds as highly potent and selective Dyrk1A inhibitors. Part I: Benzamide and benzylamide derivatives

Sarah S. Darwish, Mohammad Abdel‐Halim, Mohamed Salah, Walter Becker, Matthias Engel

European Journal of Medicinal Chemistry · 2018 · 24 citations · 50 references

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50

The specificities of protein kinase inhibitors: an update

Jenny Bain, Hilary McLauchlan, Matthew Elliott et al. · Biochemical Journal · 2003 · 1.4K citations · Full text

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Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

Theonie Anastassiadis, Sean Deacon, Karthik Devarajan et al. · Nature Biotechnology · 2011 · 926 citations · Full text

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Function of alternative splicing

Olga Kelemen, Paolo Convertini, Zhaiyi Zhang et al. · Gene · 2012 · 759 citations

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Passive Permeability and P-Glycoprotein-Mediated Efflux Differentiate Central Nervous System (CNS) and Non-CNS Marketed Drugs

Kelly M. Mahar Doan, Joan E. Humphreys, Lindsey O. Webster et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 626 citations

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Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery

Arup K. Ghose, Torsten Herbertz, Robert L. Hudkins et al. · ACS Chemical Neuroscience · 2011 · 437 citations · Full text

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