Theonie Anastassiadis

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

Theonie Anastassiadis, Sean Deacon, Karthik Devarajan et al. · Nature Biotechnology · 2011 · 926 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition

Nishita Shastri, Yu‐Chen Tsai, Suzanne E. Hile et al. · Molecular Cell · 2018 · 84 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies

Demirkan Gursel, Yvette Connell-Albert, Robert G. Tuskan et al. · Neuro-Oncology · 2011 · 51 citations · Full text

Medicine, Cancer Biology, Oncology +17

Phosphoinositides Are Essential Coactivators for p21-Activated Kinase 1

Todd I. Strochlic, Julien Viaud, Ulrike Rennefahrt et al. · Molecular Cell · 2010 · 49 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

A Highly Selective Dual Insulin Receptor (IR)/Insulin-like Growth Factor 1 Receptor (IGF-1R) Inhibitor Derived from an Extracellular Signal-regulated Kinase (ERK) Inhibitor

Theonie Anastassiadis, Krisna C. Duong‐Ly, Sean Deacon et al. · Journal of Biological Chemistry · 2013 · 19 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16